ResearchJuly 14, 2026

Understand your health through biomarkers

The first step to understanding your health is recognizing what kind of information a blood test, or other medical evaluation, is collecting and measuring. A biomarker, or biological marker, is a measurable indicator of a biological process or condition in the body. Biomarkers may include molecular measures obtained from biological samples such as blood or tissue, as well as physiological measures like blood pressure or heart rate.

VOLO Health created the Biomarker Reference Guide (BRG) to give individuals and their healthcare providers additional insights related to laboratory test results and other health data. The BRG contains modeled ranges of values for biomarkers that have been associated with the future prevalence of certain common age-related disease outcomes in VH statistical models of research populations. The VH team selected the health domains, such as cardiovascular health, kidney health, and metabolic health, and associated outcomes in the BRG based on the prevalence of the outcomes as well as the impacts of these outcomes on aging and overall wellness.

The information presented reflects statistical associations observed in longitudinal research populations (the UK Biobank and other U.S.-based databases).

CHECK OUT THE VOLO HEALTH BIOMARKER REFERENCE GUIDE.

DISCLAIMER IMPORTANT—READ FIRST The BRG and the VH modeled ranges are provided solely for informational, educational, and general-wellness purposes. The BRG is not intended to diagnose, cure, mitigate, treat, or prevent any disease or other condition, and it does not provide medical advice, individualized risk predictions, or treatment recommendations. Likewise, the BRG does not claim that any biomarker, behavior, or intervention will cure, mitigate, treat, or prevent any condition in any individual. The modeled ranges in the BRG are not clinical or laboratory reference ranges, diagnostic thresholds, or treatment recommendations. The BRG does not account for all factors relevant to health and cannot rule in or rule out the presence or absence of any disease or other medical condition.

The information provided in the BRG is derived from applying data science, such as statistical modeling and machine learning, to population datasets with known and potential limitations regarding population demographics—including geographic location, socioeconomic status, clinical setting, data collection methodology, age, gender, race, ethnic background, and potential bias in the underlying population. These limitations may affect the accuracy and generalizability of outputs across different populations or use contexts. The statistical associations described in this guide are not evidence of causation. VH’s research has not concluded that any biomarker causes, prevents, treats, mitigates, or cures any disease or condition. Any and all claims regarding the accuracy of the information, the benefits of using such information, or the predictive value of the underlying models for any individual are expressly disclaimed.

The information provided here does not consider an individual’s health conditions, medical history, or specific circumstances. This guide is not a substitute for consultation with a qualified healthcare professional or for screening or diagnostic testing. Individuals should seek advice from a qualified healthcare professional for any questions regarding diagnosis, treatment, or prevention of any disease or other medical condition. Individuals or entities using the information in this guide do so at their own risk.

Special Populations This guide is not intended for pregnant or breastfeeding women or minors. This guide relates to data models that have not been developed for, validated in, or tailored to pregnant or breastfeeding women or minors under the age of eighteen. Pregnant or breastfeeding women and parents or guardians of minors should consult with a qualified healthcare professional before using or relying on any information in this guide.

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